10 The Following Is A Problematic Solid Phase Synthesis Of The Intended Tetrapeptide Gly Ala Lys Val A Draw The Oth 1 (40.56 KiB) Viewed 17 times
10 The Following Is A Problematic Solid Phase Synthesis Of The Intended Tetrapeptide Gly Ala Lys Val A Draw The Oth 2 (40.56 KiB) Viewed 17 times
10. The following is a PROBLEMATIC solid phase synthesis of the intended tetrapeptide (Gly-Ala-Lys-Val). A) Draw the other TWO tetrapeptides that would result in the box provided. You can abbreviate any of the amino acids using their three lettered codes to save time (12 marks) NHво Reun HO. 'N DCO. Pyridine A BACH 1) TFA CH 2) HO.CZ B 1) TPA 2) HO, NH DCO, pyridine DOC. pyridine Hes NH NH CH och CHCH NDO D HE i HO NH Com HN Oly-Ala-Lys Val B) Fix the incorrect step(s) so as to produce the intended tetrapeptide: Gly-Ala-Lys-Val. You can adapt the reaction scheme accordingly. Steps are lettered for convenience if you are working on paper END OF EXAM
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