APC inactivates FVIIIa by proteolytic cleavage at which of the following sites?

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answerhappygod
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APC inactivates FVIIIa by proteolytic cleavage at which of the following sites?

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a) R313 and/or R512
b) R454 and/or R565
c) R234 and/or R554
d) R336 and/or R562
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