Consider the following reaction. What is the role of LDA? CH,COyEt 1.LDA, THF 2. CH₂CH₂Br LDA acts as an acid to protona

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Consider the following reaction. What is the role of LDA? CH,COyEt 1.LDA, THF 2. CH₂CH₂Br LDA acts as an acid to protona

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Consider The Following Reaction What Is The Role Of Lda Ch Coyet 1 Lda Thf 2 Ch Ch Br Lda Acts As An Acid To Protona 1
Consider The Following Reaction What Is The Role Of Lda Ch Coyet 1 Lda Thf 2 Ch Ch Br Lda Acts As An Acid To Protona 1 (22.95 KiB) Viewed 28 times
Consider the following reaction. What is the role of LDA? CH,COyEt 1.LDA, THF 2. CH₂CH₂Br LDA acts as an acid to protonate the carbonyl carbon to form a good electrophile. LDA acts as an electrophile and adds to the alkyl halide so it is easier to substitute. LDA acts as a base and removes a proton from the alpha carbon to form the enolate. LDA acts as a nucleophile and is substituted by the THF. CH₂CH3 CHCO₂Et
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