- Which drug is eliminated linearly? (1 Point) O Vancomycin O Gentamicin O Phenytoin Two of the above O All of the above
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- Which drug is eliminated linearly? (1 Point) O Vancomycin O Gentamicin O Phenytoin Two of the above O All of the above
GS is a 45 year old female who weighs 270 pounds and is 5'8 feet tall is admitted for a deep tissue abscess in her right knee. Cultures were obtained in clinic prior to admission and are already growing Pseudomonas. Tobramycin and Cipro are being initiated. In clinic today GS had a normal BUN/Scr of 14/1.1. Which is the most accurate method for calculating creatinine clearance in GS? (1 Point) Cockroft & Gault Equation 24 hour urine collection utilizing the measured Creatinine Clearance equation Schwartz Equation Sawchuk-Zaske Method
Routine lab for anticoagulation monitoring is required for (1 Point) O warfarin enoxaparin dabigatran apixaban Which medication may have decreased dialysis clearance due to increased protein binding? (N%)= % protein bound (1 Point) Cefepime (19%) Ampicillin (15%) Tobramycin (30%) Phenytoin (95%)
- What does the phrase "Start low and go slow" mean when dosing medications for older adults? (1 Point) Using a lower dose will adjust for reduced volume of distribution of lipophilic drugs Using a lower dose and titrating up slowly will adjust for hepatic and renal clearance changes Using a lower dose for hydrophilic drugs will adjust for increased total body water Giving a drug less frequently will adjust for a slow GI transit time 2. Which medication would cause tacrolimus levels to increase? (1 Point) Fluconazole Phenytoin Prednisone Mycophenolate