A 25-year-old woman comes to the physician because of a 2-day history of fever, malaise, and a rash. She had a single pa
Posted: Mon Apr 11, 2022 7:57 am
A 25-year-old woman comes to the physician because of a 2-day history of fever, malaise, and a rash. She had a single painless lesion on her labia 3 weeks ago, but it resolved spontaneously. She is sexually active, but she and her partner do not use condoms consistently. Her temperature is 38°C (1004°F). Physical examination shows a dtffuse erythematous rash that includes the palms and soles. A sensitive but nonspecific rapid serologic screening test that uses which of the following reagents is most likely to support a diagnosis?
A) Antitreponemal antibody on beads
B) Dead commensal treponemes on beads
C) Live Treponema pal/idum on glass slides
D) A phospholipid (cardiolipin) on charcoal particles
E) Soluble fluorescent treponemal antibodies
F) Treponemal antigens on ELISA plates
A) Antitreponemal antibody on beads
B) Dead commensal treponemes on beads
C) Live Treponema pal/idum on glass slides
D) A phospholipid (cardiolipin) on charcoal particles
E) Soluble fluorescent treponemal antibodies
F) Treponemal antigens on ELISA plates