A 25-year-old woman comes to the physician because of a 2-day history of fever, malaise, and a rash. She had a single pa

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A 25-year-old woman comes to the physician because of a 2-day history of fever, malaise, and a rash. She had a single painless lesion on her labia 3 weeks ago, but it resolved spontaneously. She is sexually active, but she and her partner do not use condoms consistently. Her temperature is 38°C (1004°F). Physical examination shows a dtffuse erythematous rash that includes the palms and soles. A sensitive but nonspecific rapid serologic screening test that uses which of the following reagents is most likely to support a diagnosis?


A) Antitreponemal antibody on beads
B) Dead commensal treponemes on beads
C) Live Treponema pal/idum on glass slides
D) A phospholipid (cardiolipin) on charcoal particles
E) Soluble fluorescent treponemal antibodies
F) Treponemal antigens on ELISA plates