8. Phosphofructokinase-1 (PFK-1) catalyzes the second matbolically irreversible reaction in glycolysis. It is considered

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8 Phosphofructokinase 1 Pfk 1 Catalyzes The Second Matbolically Irreversible Reaction In Glycolysis It Is Considered 1 (30.66 KiB) Viewed 19 times

8. Phosphofructokinase-1 (PFK-1) catalyzes the second matbolically irreversible reaction in glycolysis. It is considered the the main flux controlling enzyme for glycolysis. This means that the catalytic rate of PFK-1 is the primary determinant of how quickly metabolites flow through glycolysis. a. Propose an explanation for why PFK-1, not hexokinase, is considered the main flux controlling enzyme for glycolysis. b. Draw a graph showing the activity of PFK-1 in the presence and absence of ATP. Your graph should include two curves on the same set of axes. Axes should be labeled as specifically as possible.