You mutate a heterotrimeric G protein so that the alpha subunit can no longer dissociate from the beta and gamma subunit

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You Mutate A Heterotrimeric G Protein So That The Alpha Subunit Can No Longer Dissociate From The Beta And Gamma Subunit 1 (27.56 KiB) Viewed 11 times

You mutate a heterotrimeric G protein so that the alpha subunit can no longer dissociate from the beta and gamma subunits. How would this mutation affect G protein-coupled receptor (GPCR) signaling? The signal transduction pathway would activate normally, but be unable to terminate properly. O Cyclic AMP levels would rise uncontrollably. O Adenylyl cyclase would remain activated. The signal transduction pathway could not activate in response to ligand binding. The ligand would not bind to the GPCR. Submit Request Answer