Question Completion Status: QUESTION 19 Based on the data and information in Figure 2, answer al carts of this question
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Question Completion Status: QUESTION 19 Based on the data and information in Figure 2, answer al carts of this question
Question Completion Status: QUESTION 19 Based on the data and information in Figure 2, answer al carts of this question a) What protein is inhibited by BI 2536? (2 pts) b) Which cell line is resistant to induction of apoptosis by B 25362 (2 pts) c) What is the minimum dose of BI 2536 that causes at least 40% apoptosis in non-resistant cell lines? (2) 44 100 Apoptosis (%, 72h) 80 60 40 20 0 SUMM OMDA-MB-231 GHRS GB7474-M1 CD 1 5 10 25 50 100 B2536 (M) points Save A Figure 2. Effect of PLKI inhibition on breast cancer cell apoptosis. Percentage of apoptosis of different breast cancer cells caused by B2 2536 after 72 hours (Reference: DOI: 10.1186/ber3107)