- Please Read The Questions And Answers Only Questions 7 8 9 1 (96.79 KiB) Viewed 10 times
please read the questions and answers ONLY Questions 7,8,9
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please read the questions and answers ONLY Questions 7,8,9
please read the questions and answers ONLY Questions 7,8,9
CRITICAL THINKING EXERCISES Exercise 8.1 A sample from a 55-year-old Caucasian male donor demonstrated a positive antibody screen during routine processing testing. The antibody identification panel's results are shown. The laboratory uses LISS as an antibody enhancement and anti-IgG for the AHG reagent. Refer to the panel to answer the following questions: Cell 1 R1R1 2 R1R1 3 R2R2 4 rºr 5 rr 6 rr 7 RORO 8 rr 9 rr 10 R1R1 Patient cells LISS P1 Lewis Lutheran Kell Duffy Kidd DCECefCWMNSS P1 Le Le Lu Lu Kk Fy" Fyb Jk JK IS 37 IgG CC ++0000+++++0+0+++0+0001+ ++00+0++00++0+0+0+0+++000 +0+0000+0+++00++++0+000 00++++0+0+0+0+0+0+0++002+ 000+0+++++0+0+0+0+0001+ 000+++++++++00+0+00001+ +00+0+00000+0+++++0+000V 000+++0+0+++000+0+0+0+001+ 000++++++00+00+0++++0002+ +00+0+0+0+0+0+0+0+0000V Rh MNSS 1. What phase in the panel is showing antibody reactivity? 2. What does this reaction phase suggest regarding the immunoglobulin class of antibody? 3. Is this antibody an alloantibody or an autoantibody? Defend your answer. 4. What is the antibody's most likely specificity? 5. Are there antibodies that cannot be ruled out on this panel? 6. What additional testing should be performed to verify the specificity? 7. What caused the antibody production in this donor? 8. Referring to the antigram, which panel cell or cells are homozygous for the S antigen? 9. Which panel cell is probably U-negative? Defend your answer. 000r
CRITICAL THINKING EXERCISES Exercise 8.1 A sample from a 55-year-old Caucasian male donor demonstrated a positive antibody screen during routine processing testing. The antibody identification panel's results are shown. The laboratory uses LISS as an antibody enhancement and anti-IgG for the AHG reagent. Refer to the panel to answer the following questions: Cell 1 R1R1 2 R1R1 3 R2R2 4 rºr 5 rr 6 rr 7 RORO 8 rr 9 rr 10 R1R1 Patient cells LISS P1 Lewis Lutheran Kell Duffy Kidd DCECefCWMNSS P1 Le Le Lu Lu Kk Fy" Fyb Jk JK IS 37 IgG CC ++0000+++++0+0+++0+0001+ ++00+0++00++0+0+0+0+++000 +0+0000+0+++00++++0+000 00++++0+0+0+0+0+0+0++002+ 000+0+++++0+0+0+0+0001+ 000+++++++++00+0+00001+ +00+0+00000+0+++++0+000V 000+++0+0+++000+0+0+0+001+ 000++++++00+00+0++++0002+ +00+0+0+0+0+0+0+0+0000V Rh MNSS 1. What phase in the panel is showing antibody reactivity? 2. What does this reaction phase suggest regarding the immunoglobulin class of antibody? 3. Is this antibody an alloantibody or an autoantibody? Defend your answer. 4. What is the antibody's most likely specificity? 5. Are there antibodies that cannot be ruled out on this panel? 6. What additional testing should be performed to verify the specificity? 7. What caused the antibody production in this donor? 8. Referring to the antigram, which panel cell or cells are homozygous for the S antigen? 9. Which panel cell is probably U-negative? Defend your answer. 000r