7. Because nonbiologic DMARDs were no longer effective in Jessica Q's disease, the rheumatologist decided to add a biolo

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7 Because Nonbiologic Dmards Were No Longer Effective In Jessica Q S Disease The Rheumatologist Decided To Add A Biolo 1 (36.45 KiB) Viewed 28 times

7. Because nonbiologic DMARDs were no longer effective in Jessica Q's disease, the rheumatologist decided to add a biologic DMARD to the therapy. Which of the following statements best explains a primary advantage of biologic over nonbiologic DMARDS a. they have a lower risk of adverse effects b. their therapeutic effect occurs after 2 to 3 days of therapy c. they can improve RA resistance to nonbiologic DMARDS d. they can be easily administered by oral route e, they can reverse the existing joint damage 8. Etanercept (Enbrel) was prescribed for Jessica Q. Which of the following molecular actions would most likely mediate the therapeutic effectiveness of this drug in the patients' RA? a. Decreased gene expression of TNF-a b.blockade of TNF-a receptors c. binding to TNF-ain the extracellular fluid d. stimulation of TNF-a metabolism e. increased renal excretion of TNF-a