Drugs receptors 1. Drugs should be highly water soluble to bind to intracellular receptors like estrogen 2. G, protein c

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Drugs Receptors 1 Drugs Should Be Highly Water Soluble To Bind To Intracellular Receptors Like Estrogen 2 G Protein C 1 (104.04 KiB) Viewed 58 times

Drugs receptors 1. Drugs should be highly water soluble to bind to intracellular receptors like estrogen 2. G, protein coupled receptors bind to plasma membrane and when activated, stimulate adenyl cyclase to convert ATP to CAMP 3. Ligand gated ion channel is one of tyrosine kinase receptors 4. Antacid act through Gi protein coupled receptor About Adverse effects EXCEPT 1. Can be due direct drug mechanism of action 2. It can be immunological reaction that has no relation with it mechanism of action 3. It could be gene polymorphism that affect drug response 4. If appear the drug should be stopped immediately All about antagonists is true EXCEPT 1. Partial agonist has lower potency than the full agonist so it can be used as antagonist 2. Physiological antagonist can reverse agonist effect through different pathway