Drug Binding: The following small molecules were constructed by
a team of medicinal chemists from Arizona State University. Their
collaborators from ASU Pharma are interested in understanding how
they bind to the active site of a protein they have been studying
for treatment of hypertension. Based on the structure of the active
site below and your knowledge of intermolecular interactions,
please indicate the optimal binding pose for each small molecule
and provide a rationale.
Drug Binding The Following Small Molecules Were Constructed By A Team Of Medicinal Chemists From Arizona State Universi 1 (172.72 KiB) Viewed 54 times
Drug Binding: The following small molecules were constructed by a team of medicinal chemists from Arizona State University. Their collaborators from ASU Pharma are interested in understanding how they bind to the active ute of a protein they have been studying for treatment of hypertension. Based on the structure of the active site below and your knowledge of intermolecular interactions, please indicate the optimal binding pose for each small molecule and provide a rationale. a) Me HO HEN b) Me HO" Binding we of unidentified protein Winding wheel deputa OH c) НО binding site of unidentified protein binding stel unidentified protein
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