Tertiary alcohols with two identical alkyl groups attached to the alcohol carbon can be made either from an ester and tw

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Tertiary alcohols with two identical alkyl groups attached to the alcohol carbon can be made either from an ester and tw

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Tertiary Alcohols With Two Identical Alkyl Groups Attached To The Alcohol Carbon Can Be Made Either From An Ester And Tw 1
Tertiary Alcohols With Two Identical Alkyl Groups Attached To The Alcohol Carbon Can Be Made Either From An Ester And Tw 1 (118.75 KiB) Viewed 94 times
Tertiary alcohols with two identical alkyl groups attached to the alcohol carbon can be made either from an ester and two moles of a Grignard reagent, or from a ketone and one mole of a Grignard reagent. Use retrosynthetic analysis to suggest one path of each type to synthesize 2-phenyl-2-propanol (or 2-phenylpropan-2-ol). OH H30+ Reagent 1 + Reagent 2 → al Route 1: Select an Ester, and an appropriate Grignard, to give 2-phenyl-2-propanol (or 2-phenylpropan-2-ol) after reaction and an aqueous workup. Route 2: Select a ketone, and an appropriate Grignard, to give 2 2 2-phenyl-2-propanol (or 2-phenylpropan-2-ol) after reaction and an aqueous workup.
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