You have a patient in your clinic presenting symptoms of cystic fibrosis. You screen their CFTR gene for mutations, and

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answerhappygod
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You have a patient in your clinic presenting symptoms of cystic fibrosis. You screen their CFTR gene for mutations, and

Post by answerhappygod »

You have a patient in your clinic presenting symptoms of cystic
fibrosis. You screen their CFTR gene for mutations, and find the
following list:
CFTR 320 L V
CFTR 341 S W
CFTR 528 E D
CFTR 976 F Q
CFTR 1235 S R
Which mutation(s) are likely causing cystic fibrosis in this
patient?
You also sequence a newborn family member of this patient. They
have all of these same mutations, other than the one at position
976, and no other mutations in CFTR. Do you predict this person
will develop cystic fibrosis? Explain why.
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