explains the synthesis of Isoleucine. Explain the
materials used, as well as the
instruments/apparatus and
chemical/reagents
- Make A Laboratory Procedure In Which It Explains The Synthesis Of Isoleucine Explain The Materials Used As Well As The 1 (41.84 KiB) Viewed 259 times
- Make A Laboratory Procedure In Which It Explains The Synthesis Of Isoleucine Explain The Materials Used As Well As The 2 (50.55 KiB) Viewed 259 times
- Make A Laboratory Procedure In Which It Explains The Synthesis Of Isoleucine Explain The Materials Used As Well As The 3 (45.43 KiB) Viewed 259 times
- Make A Laboratory Procedure In Which It Explains The Synthesis Of Isoleucine Explain The Materials Used As Well As The 4 (50.42 KiB) Viewed 259 times
B. Second Step 2-Methylbutanoic acid reacts with thionyl chloride (SOCh), diazomethane (CH2N2), and silver oxide (Ag20, H2O) to produce 3-Methylpentanoic acid. This reaction is known as Arndt-Eistert reaction. OH 1. SOCI 3. CH2N2 2. Ag20, H2O OH 2-Methylbutanoic acid 3-Methylpentanoic acid Figure 3. Second step of the synthesis for Isoleucine
C. Third Step: 3-Methylpentanoic acid reacts with bromine (Bra) in the presence of red-phosphorus (Red-P) to form 2-Bromo-3-methylpentanoic acid. O O Red-P, Br2 u ОН OH Br 2-Bromo-3-methylpentanoic acid 3-Methylpentanoic acid Figure 4. Third step of the synthesis for Isoleucine
D. Fourth Step: 2-Bromo-3-methylpentanoic acid reacts with 2 molecules of ammonia (2 NH3), followed by hydrolysis to form Isoleucine ((2-amino-3-methylpentanoic acid)). H2O + 2 NH3 + 2 NH4B ОН Br + NH3 Isoleucine 2-Bromo-3-methylpentanoic acid Ammonium bromide Figure 5. Fourth step of the synthesis for Isoleucine