A case-control study was undertaken to identify whether the risk of a major depressive disorder was increased by a past

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A Case Control Study Was Undertaken To Identify Whether The Risk Of A Major Depressive Disorder Was Increased By A Past 1 (101.03 KiB) Viewed 89 times

A case-control study was undertaken to identify whether the risk of a major depressive disorder was increased by a past traumatic event. Researchers recruited a total of 398 men and women aged less than 40 years with a diagnosis of a major depressive disorder and 352 matched men and women without a major depressive disorder. Participants were questioned about past traumatic events. The table below presents the study findings. Major Depressive Disorder Yes Yes 43 30 Traumatic event No 355 322 398 352 <a> What is the appropriate measure of association for this study? (1 mark) <b> Please calculate this measure (showing calculations). (1 mark) <c> Please interpret the result. (1 mark) <d> The researchers submitted a journal article based on the study. A reviewer of the article identified that five people from the control group who had been exposed to a past traumatic event had withdrawn from the study prior to providing data. She questioned the validity of the findings. What fundamental epidemiological issue does this relate to? (1 mark) <e> What was the likely effect of the 5 participants who chose to withdraw from the study on the measure of association? Please explain this with reference to the null value. (1 mark) 2 No