What evidence would be needed in a study aimed at determining if natural selection is acting on cholesterol levels in hu

[answerhappygod]

What evidence would be needed in a study aimed at determining if
natural selection is acting on cholesterol levels in humans?
Individuals who have high cholesterol levels in their blood have
fewer children on average than those who do not.
Individuals who have high cholesterol levels in their blood have
more children on average than those who do not.
Individuals who have low cholesterol levels in their blood have
children earlier in life than those who do not.
Individuals who exercise daily have lower cholesterol levels in
their blood than those who do not and have fewer children on
average.
Individuals who have a genetic tendency to have low cholesterol
levels in their blood have fewer children on average than those
lacking that tendency.