n a randomized controlled trial of a treatment for multiple sclerosis, 450 participants were randomized to an experiment

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n a randomized controlled trial of a treatment for multiple
sclerosis, 450 participants were randomized to an experimental drug
or a standard of care treatment and followed for seven years. The
primary outcome of the trial was all-cause mortality, which was
assessed using death certificates. The 225 participants in the
experimental drug arm accumulated a mean of four person-years of
follow-up, while the 225 participants in the standard of care arm
accumulated a mean of six person-years of follow-up. There were 25
total deaths, 14 of which were in the experimental drug arm. What
was the risk of death among participants in the experimental arm,
relative to those in the standard of care arm?
A. 0.52
B. 0.85
C. 1.27
D. 1.91
E. More information would be needed to calculate this
answer.
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