CAN YOU PLEASE ANSWER THIS BIOINFORMATIC QUESTION ASAP! John Louis has been suffering from pancreatic cancer. His DNA ha

[answerhappygod]

CAN YOU PLEASE ANSWER THIS BIOINFORMATIC QUESTION ASAP!
John Louis has been suffering from pancreatic cancer.
His DNA has been isolated and ATR gene was sequenced with his
request. Sequence of the patient’s ATR gene is provided below and
the reference sequence`s accession number is NM_001184.4
.
Patient`s sequence
>patient ATR
ctgatcttgc tgccaaagca agccctgcag cttctgctct cattcgaact
ttaggaaaac aattaaatgt caatcgtaga gagattttaa taaacaactt caaatatatt
ttttctcatt tggtctgttc ttgttccaaa gatgaattag aacgtgccct tcattatctg
aagaatgaaa cagaaattga actggggagc ctgttgagac aagatttcca aggattgcat
aatgaattat tgctgcgtat tggagaacac tatcaacagg tttttaatgg tttgtcaata
cttgcctcat ttgcatccag tgatgatcca tatcagggcc cgagagatat cgtatcacct
gaactgatgg ctgattattt acaacccaaa ttgttgggca ttttggcttt ttttaacatg
cagttactga
gctctagtgt tggcattgaa gataagaaaa tggccttgaa cagtttgatg
tctttgatga agttaatggg acccaaacat gtcagttctg tgagggtgaa gatgatgacc
acactgagaa ctggccttcg attcaaggat gattttcctg aattgtgttg cagagcttgg
gactgctttg ttcgctgcct ggatcatgct tgtctgggct cccttctcag tcatgtaata
gtagctttgt tacctcttat acacatccag cctaaagaaa ctgcagctat cttccactac
ctcataattg
a. Are there any changes in nucleic acid and amino acid
sequences? If yes please explain the location(s) and change(s). (3
points)
b. Does this change affect the protein domains? Explain in
detail. (3 points)
c. Based on your analysis in section (a) and (b), does this
variation affect the protein function or not? Explain your answer.
(2 points)
d. Which program(s)/database(s) have you used to answer this
question, list respectively. (1 point)