1. Onabotulinumtoxin A is a compound that weights 150,804 grams/mol, has thousands of hydrogen bonds (donors and accepto
Posted: Thu Dec 02, 2021 5:18 am
1. Onabotulinumtoxin A is a compound that weights 150,804
grams/mol, has thousands of hydrogen bonds (donors and acceptors),
and thus does not adhere to Lipinski’s Rule of 5, however, is a
widely used drug to treat various conditions like chronic
migraines, spasms of the muscles of the neck, and urinary
incontinence. Look up and state how Onabotulinumtoxin A is
administered and one of its commercial names.
2. Explain in 2-3 sentences how the pharmaceutical from Question
1 can be a successful drug candidate and is widely used, but does
not fit the Rule of 5.
grams/mol, has thousands of hydrogen bonds (donors and acceptors),
and thus does not adhere to Lipinski’s Rule of 5, however, is a
widely used drug to treat various conditions like chronic
migraines, spasms of the muscles of the neck, and urinary
incontinence. Look up and state how Onabotulinumtoxin A is
administered and one of its commercial names.
2. Explain in 2-3 sentences how the pharmaceutical from Question
1 can be a successful drug candidate and is widely used, but does
not fit the Rule of 5.