questions below. 1. Refer to the table below to compute the Age Specific rates. Whites Blacks Age Other Population Years Cases Population Age Specific Cases Population Cases Specific <50 3,616 7,420,076 1,415 3,344,874 662 1,586,388 50-54 1,913 830,549 690 293,626 286 148,548 55-59 2,094 736,737 692 244,829 293 131,258 60-64 2,043 567,178 577 162,834 194 89,008 65-69 1,788 400,785 443 111,761 2,066 69,068 70+ 4,940 1,210,138 1,026 266,941 429 177,188 2. Describe the extent of the public health problem of female breast cancer according to place. TABLE 4-12 Female Crude Malignant First Primary Breast Cancer Incidence Rates in San Francisco and the Metropolitan Areas of Detroit and Atlanta According to Selected Racial Groups, 2013-2015 American Indian/ Asian or Pacific Alaska Native Islander White Black Location Rate per 100,000 Rate per 100,000 Rate per 100,000 Rate per 100,000 San Francisco 165.6 139.9 46.8 129.1 Detroit (metropolitan) 177.5 145.6 73.8 88.7 Atlanta (metropolitan) 156.7 119.7 22.1 76.0 Three areas combined 167.8 131.4 47.7 116.8 Data from Surveillance, Epidemiology, and End Results (SEEF) Program (www.seet.cancer.gov) SEER "Stat Database: Incidence- SEER 18 Regs Research Data + Hurricane Katrina Impacted Louisiana Cases, Nov 2017 Sub (2000-2015) <Katrina/Rita Population Adjustment>-Linked To County Attributes-Total U.S., 1969-2016 Counties, National Cancer Institute, DCCPS, Surveillance Research Frogram, released April 2018, based on the November 2017 submission. 3. Consider this data set showing 9 participants' total cholesterol levels. 185 225 240 196 175 180 194 147 223 a. Compute the sample mean. Age Specific
b. Compute the sample standard deviation. c. Compute the median. 4. Go to the U.S. Census Bureau's site on international demographic data. The link is provided in this week's reading title Website: International Data Base (IDB). Once at this site, click the tab "Select Report" and then choose "Population Pyramid Graph." Select the year "2020" and "United States." Then select the "Submit" tab. How does the age distribution compare between Afghanistan and the United States? Answer must be at least 4 complete sentences.
Incidence Rate = New cases occurring during a given time period Population at risk during the same time period x 10² hortality rate is the total number of deaths reported during a given e interval divided by the population from which the deaths occurred. calculated as: Mortality Rate = Deaths occurring during a given time period Population from which deaths occurred X10²
New cases occurring during a short time period Attack Rate = x 100 Population at risk at the beginning of the time period describe diseases or events that affect a larger proportion of the population than the con the rate base for the attack rate is 100. al illness was reported to the District Health Officer in Syracuse, New York.25 The illness to cases of illness in a place and time above what is normally expected. Outbreak refers The investigation of the outbreak involved first constructing a line listing of those at the pi illness resulted, date of onset, time of onset, and whether selected foods were eaten. At vanilla ice cream, 43 were ill and 11 were not ill, yielding an attack rate of 80%. That atta number of individuals who ate vanilla ice cream (54) in the denominator. Of those who di es is 5.7, indicating that those who ate the vanilla ice cream were 5.7 times more likely to he attack rate of those who ate vanilla ice cream (80%) in the numerator and the attack ra urring among contacts of known cases. This incidence rate is known as the secondary a New cases among contacts of primary cases during a short time period SAR = x 100 Population at beginning of time period - (Primary cases) he time period yields the at-risk population. For example, in a daycare center, 40 children secondary attack rate is as follows: SAR = 120-40 480 - 40 x 100 = 18.2 ents is prevalence, which is the frequency of existing cases of a health-related state or e a point in time. Point prevalence is a proportion and is calculated as follows: Existing cases of a disease or Point Prevalence = event at a point in time Total study population ×100 at a point in time or event during a time period. For example the period prevalence of arthritis in a given yo
Confidence Intervals When a rate is based on sample data, the sample rate is an estimate of the population rate. Confidence intervals are used to measure the precision of a sample rate. A confidence interval is the range of values in which the population rate is likely to fall. By convention, 95% confidence intervals are used to indicate a range in which the investigators are 95% confident that the true population rate lies. The formula to calculate a 95% confidence interval for an incidence rate is: Rate ±1.96√/Rate(1 - Rate)/n Rate refers to the attack rate (or the cumulative incidence rate), and n equals the population at risk. When computing the confidence interval, make sure the rate is in decimal form (i.e., not multiplied by a rate base). After the confidence interval is computed, multiply the lower and upper limits by a relevant rate base. For example, suppose a random sample of 100 workers at a steel plant were selected and monitored over time for respiratory problems. If 25 of these workers complained of respiratory problems after 1 month of follow-up, such that the rate is 25 per 100, the 95% confidence interval for the rate is: 0.25±1.96√√0.25(1-0.25)/100 = 0.165, 0.335; 16.5-33.5 per 100 Thus, we are 95% confident that the true rate of respiratory problems is in the interval 16.5-33.5 per 100 steel workers. For a person-time incidence rate, the formula is modified as follows: Rate ± 1.96 Number of new cases/(person-time at risk)2 To illustrate, let's refer again to the data in Table 4-4. To calculate the 95% confidence interval for the 40- to 49-year male rate of first primary malignant cancer, we apply the formula as follows: 33,706 = 0.001901, 0.001942 √(17,544,979)² 0.001921±1.96, Thus, we are 95% confident that the true 40-to 49-year male rate of first primary malignant cancer during 2013-2015 is in the interval 190.1-194.2 per 100,000 person-years. Finally, an approximate 95% confidence interval for the SMR can be calculated if we can appropriately assume a normal distribution.28 The formula is: SMR ±1.96√/SMR/Expected Based on the SMR example presented above, 0.848 0.848±1.96, = 0.846, 0.850 √719,276 So we are 95% confident that the true SMR reflecting the ratio of female-to-male malignant cancer cases is between 0.846 and 0.850.
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