In receptor mediated endocytosis, the receptors (such as the low-density lipoprotein, LDL, receptor) can enter the coate

[answerhappygod]

In receptor mediated endocytosis, the receptors (such as
the low-density lipoprotein, LDL, receptor) can enter the coated
pits even when they don't bind their ligands.
T or F
The mannose 6-phosphate (M6P) receptors are crucial for
delivering lysosomal proteins to lysosomes, while the KDEL
receptors are important to send the ER resident proteins back to
the ER. Which of the following statements is INCORRECT
regarding the M6P receptors and the KDEL receptors?
They both shuttle back and forth between different
membrane-enclosed compartments.
They are both transmembrane proteins.
They both release their soluble binding targets at a
lower pH.
They both prevent the escape of proteins to the cell
exterior by the “default” pathway.
The G-proteins associated with GPCRs are made up
of three subunits. In order to become active they must do
which of the following?
The gamma subunit must hydrolyze GTP.
They must associate with the GPCR.
They must bind to GDP.
The alpha subunit must bind to GTP.
PI3K is a cancer activating molecule because of what
molecular function?
It works to directly phosphorylate cyclin dependent
kinases and thus actives the cell cycle.
It works to phosphorylate membrane lipids which can then
recruit signaling molecules for the initiation of a phosphorylation
cascade.
It works at the cell membrane to facilitate the
inactivation of mTOR.
All the provided answers are correct.
Please answer all questions no need for explanation ASAP.