In cancers the Ras pathway activation happens because a translocation between the Ras gene and the Abl kinase cause acti

[answerhappygod]

In cancers the Ras pathway activation happens because
a translocation between the Ras gene and the Abl kinase cause activation of the MAP kinase pathway.
a missense mutation in one copy of the Ras gene results in hyperactive binding to GTP.
there are mutations in two copies of the Ras gene which are needed in order to activate receptor binding.
receptor tryosine kinase signaling is activated through signal transduction caused by a hyperactive binding to GDP