42. of 68 (undefined) View Mark for Which of the following would you expect to occur when hepatocytes expressing the glu

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42 Of 68 Undefined View Mark For Which Of The Following Would You Expect To Occur When Hepatocytes Expressing The Glu 1 (30.68 KiB) Viewed 11 times

42. of 68 (undefined) View Mark for Which of the following would you expect to occur when hepatocytes expressing the glucocorticoid receptor (GR) are cultured in the presence of cortisol (a glucocorticoid)? Scratch out (A) GR binds cortisol on the cell surface and stimulates adenylate cyclase by a G protein-coupled mechanism. Scratch out (B) Binding of cortisol to cytoplasmic GR results in GR translocation to the nucleus, where it binds Glucocorticoid Response Elements in the DNA. Scratch out (C) Cortisol diffuses into the cell nucleus and intercalates into DNA, thus facilitating transcription. Scratch out (D) GR cannot be involved in transcriptional regulation because it is a hormone receptor