1. The first step in the payoff phase of glycolysis is catalyzed by the enzyme glyceraldehyde 3-phosphate dehydrogenase,
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1. The first step in the payoff phase of glycolysis is catalyzed by the enzyme glyceraldehyde 3-phosphate dehydrogenase,
1. The first step in the payoff phase of glycolysis is catalyzed by the enzyme glyceraldehyde 3-phosphate dehydrogenase, an enzyme that contains a nucleophilic cysteine playing a central role in the reaction. A) Why is the reaction deemed the first "payoff" reaction in the glycolytic sequence? B) Draw a reasonable arrow-pushing mechanism for the following step in the reaction of glyceraldehyde 3- phosphate dehydrogenase. Use general bases and acids as needed: HH OPO,2 OPO₂² -OH SH NH₂ NH₂ OH
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