A key step in glycolysis is the oxidation of glyceraldehyde-3-phosphate to 1,3-bisphosphoglycerate. Several things happe

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A Key Step In Glycolysis Is The Oxidation Of Glyceraldehyde 3 Phosphate To 1 3 Bisphosphoglycerate Several Things Happe 1 (129.29 KiB) Viewed 44 times

A key step in glycolysis is the oxidation of glyceraldehyde-3-phosphate to 1,3-bisphosphoglycerate. Several things happen during this reaction including an oxidation, a reduction and addition of inorganic phosphate to the substrate. During this reaction NADgets reduced at the same time as glyceraldehyde-3-phosphate gets oxidized. What would happen if NAD were not available for this reaction? Glyceraldehyde-3-phosphate would not get oxidized, but phosphorylation to 1,3-bisphosphoglyceraldehyde would occur and that substrate could provide sufficient high energy phosphates to drive the substrate-level phosphorylation of ADP to ATP. Glyceraldehyde-3-phosphate would still get oxidized, but NADH would not be formed. O Glycolysis and its associated substrate level phosphorylation would stop A cell would switch over to anaerobic respiration