Question 22 The Ames Assay uses an auxotrophic Salmonella strains with loss-of-function mutations in the hisG gene. The

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Question 22 The Ames Assay Uses An Auxotrophic Salmonella Strains With Loss Of Function Mutations In The Hisg Gene The 1 (28.82 KiB) Viewed 41 times

Question 22 The Ames Assay uses an auxotrophic Salmonella strains with loss-of-function mutations in the hisG gene. The loss-of-function mutations could either be missense or nonsense mutations. The reversion of the hisG gene to its wild type sequence by a mutagen could result from a mutation, which would allow Salmonella to grow on media lacking histidine. missense nonsense Inversion silent frameshift