1. Oxidative decarboxylation of pyruvate and the TCA cycle in muscles are stimulated by increased aerobic exercise. The

[answerhappygod]

1. Oxidative decarboxylation of pyruvate and the TCA cycle
in muscles are stimulated by increased aerobic exercise. These
processes operate only when O2 is present, although oxygen does not
participate directly in these processes. Explain why oxidative
decarboxylation of pyruvate is activated under aerobic conditions.
For the answer: a) describe the overall reaction catalyzed by the
pyruvate dehydrogenase complex (PDH) and its regulation; b) оutline
the intermediates and enzymes of the TCA cycle; c) explain the
relationship between the reactions of PDH and the TCA cycle and the
respiratory chain