Need help, with this Bio - chemistry problem. Please, detail explanation...
Figure 2 (a) presents the results of lanmodulin in the absence and presence of the lanthanide ion, using the circular dichroism technique. Explain the conformational changes observed in lanmodulin when it is titrated with the lanthanide ion.
Figure 2 (b) presents titrations that were performed on lanmodulin with different metal ions from the lanthanide family, and also included the Ca2+ ion as part of the study. Explain the difference that was observed when comparing the results obtained with the lanthanides versus the Ca2+ ion.
Need Help With This Bio Chemistry Problem Please Detail Explanation Figure 2 A Presents The Results Of Lanmodu 1 (72.66 KiB) Viewed 38 times
a a 500 0 O equiv. La" -500 [O] (deg cm² dmol') 10-3 -1000 -1500 4-8 equiv. La -2000 250 260 200 210 220 230 240 Wavelength (nm) b 1400 1200 1000 Ln'". La-Lu, Y 800 -A[0]222nm (deg cm2 dmol-') <10-3 600 400 200 Call 0 0 2. 00 8 4 6 Equiv. metal ion Figure 2. LanM undergoes a conformational change selectively in the presence of Ln'". (A) CD spectra of LanM (20 șM) in the presence of 0–8 equiv of La". (B) Magnitude of molar ellipticity change for CD titrations of LanM (20 uM) with 0–8 equiv of Ln'" ions (La!"- Lu", except Pm", as well as Yill) and with Ca". . - 1
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