Question 1. It has been observed that an active pharmaceutical ingredient becomes less soluble in water as it changes to

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Question 1 It Has Been Observed That An Active Pharmaceutical Ingredient Becomes Less Soluble In Water As It Changes To 1 (50.44 KiB) Viewed 42 times

Question 1. It has been observed that an active pharmaceutical ingredient becomes less soluble in water as it changes to a less soluble polymorph in response to pressure. a) Discuss a suitable granulation process for this drug. b) Wet granulation usually involves a drying step to reduce the amount of moisture in the formulation. Discuss how drying is achieved using a fluidised bed dryer and its advantages over an oven tray dryer. c) Discuss the impact of the moisture content of air on a drying process. This should include how this could be controlled to ensure drying efficiency.