BACE1 gene is a target of the miR-425 microRNA. When miR-425 is expressed in cultured cells, BACE1 protein levels are re
Posted: Tue May 17, 2022 6:48 pm
BACE1 gene is a target of the miR-425 microRNA. When miR-425 is expressed in cultured cells, BACE1 protein levels are reduced. If you treat your cells (which do express miR-425) with an inhibitor of dicer, BACE1 protein levels will be higher than in untreated cells because the normal function of dicer is to remove the terminal loop fre$. If you also treated the worms with miR-425 ✓ Select) pre-miRNA, the BACE1 protein levels woul be higher than in untreated cells would be lower than in untreated cells would be about the same as in untreated cells