Recall that the enzyme CYP2D6 changes codeine to morphine and that the enzyme UGT1A converts morphine to morphine-3-gluc

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Recall that the enzyme CYP2D6 changes codeine to morphine and that the enzyme UGT1A converts morphine to morphine-3-gluc

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Recall That The Enzyme Cyp2d6 Changes Codeine To Morphine And That The Enzyme Ugt1a Converts Morphine To Morphine 3 Gluc 1
Recall That The Enzyme Cyp2d6 Changes Codeine To Morphine And That The Enzyme Ugt1a Converts Morphine To Morphine 3 Gluc 1 (116 KiB) Viewed 98 times
Recall that the enzyme CYP2D6 changes codeine to morphine and that the enzyme UGT1A converts morphine to morphine-3-glucuronide. Also recall that morphine accumulation can be dangerous due to toxicity at higher doses. Explain how the dangers faced by a codeine prescribed individual with loss of function variants in the gene encoding CYP2D6 differ from those individuals with loss of function variants in the gene encoding UGT1A
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