• Identify the various phases of the cell cycle. • Compare and contrast the cell cycles of normal and cancer cells. Pre-

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• Identify the various phases of the cell cycle. • Compare and contrast the cell cycles of normal and cancer cells. Pre-

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Identify The Various Phases Of The Cell Cycle Compare And Contrast The Cell Cycles Of Normal And Cancer Cells Pre 1
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• Identify the various phases of the cell cycle. • Compare and contrast the cell cycles of normal and cancer cells. Pre-Lab Questions: a. What factors encourage cells to divide? b. Name at least one type of mutation which could result in cancer. List at least two unique characteristics of cancerous cells. Procedure Using the diagrams of corresponding tissues attached to this lab: 1. Fill out the data table below 2. Calculate the mitotic index for each tissue using the following equation and add it to the data table: Number of dividing cells MITOTIC INDEX (%) -x 100% Total number of cells Note: o Number of dividing cells is the sum of the number of cells in prophase, metaphase, anaphase and telophase (mitotic cells) o Total number of cells is the sum of dividing cells (above) and non-dividing cells (interphase cells)

o Data Table: Tissue Type # Cells # Cells in Interphas e # Cells in Metapha se # Cells # Cells in in Anapha Telopha se se Total #Mitotic of Index, % cells Prophas Normal stomach Cancerous stomach Normal ovary 23 Cancerous ovary Normallung Cancerous lung DISCUSSION QUESTIONS: parandush 1. Based on your data table, what is the key difference between normal and cancerous tissues illustrated in the diagrams of corresponding tissues attached to this lab? 2. When studying cell division in tissue samples, scientists often calculate a mitotic index, which is the ratio of dividing cells (those NOT in interphase) to the total number of cells in the sample. Which type of tissue would have a higher mitotic index, normal tissue or cancerous tissue? Explain and use evidence from the data you collected.lt

3. Different types of normal tissues in the human body have different rates of mitosis. From the following list, which normal tissues would you expect to have the highest mitotic index muscle, skin, kidney, or lung? Explain your answer. 4. Which type of cancer, from the ones explored in this lab, is the fastest growing? Explain your answer, using your relevant data. 5. This lab explores three common cancers. An additional form of cancer -Skin Cancer - used to be seen only in older individuals but is now seen in younger individuals, many in their early 20s. Skin cancer results from accumulated mutations to the DNA of skin cells, caused primarily by sun exposure. What factors do you think may be contributing to the increase in skin cancer among young adults?
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