1. The pentose phosphate pathway provides cancer cells with: a. Reducing power to fuel biosynthetic reactions and antiox
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1. The pentose phosphate pathway provides cancer cells with: a. Reducing power to fuel biosynthetic reactions and antiox
1. The pentose phosphate pathway provides cancer cells with: a. Reducing power to fuel biosynthetic reactions and antioxidant systems. b. Ribose for making nucleotides. c. ATP for energy. d. Acetyl-CoA for driving the tricarboxylic acid cycle and lipid biosynthesis. 2. The use of glycolysis by many cancer cells ("Warburg effect"), which generates - 3 ATP/glucose as compared to oxidative phosphorylation, which generates -36 ATP/glucose, is predominantly used by many cancer cells because: a. Cancer cells don't need as much ATP as normal cells. b. It provides the “building blocks” for the cell to double its mass in preparation for cell division. c. Although it yields less ATP, it provides a faster source of ATP production to support the cancer growth. d. Cancer cells are frequently exposed to hypoxic conditions; glycolysis allows energy metabolism to continue under hypoxia.
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