5. (10 pts) In the Hippo signaling pathway shown here YAP is a transcription factor, 14-3-3 is a scaffold protein, and M

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5 10 Pts In The Hippo Signaling Pathway Shown Here Yap Is A Transcription Factor 14 3 3 Is A Scaffold Protein And M 1 (47.89 KiB) Viewed 104 times

5. (10 pts) In the Hippo signaling pathway shown here YAP is a transcription factor, 14-3-3 is a scaffold protein, and MST1/2 and LATS1/2 are protein kinases. MSTIC LATS1/2 LATS1/2 YAP 14-3-3 (YAP expression of pro growth genes 14-3-3 degradation YAP DNA nder membrane Mutations in the gene encoding YAP that prevent its phosphorylation cause formation of tumors in the liver. How is the gene encoding YAP classified? oncogene tumor suppressor gene a. Cancer is characterized by which condition? Uncontrolled cell proliferation Controlled cell proliferation Uncontrolled degradation of the chromosome and cellular proteins Controlled degradion of the chromosome and cellular proteins b. In response to a potential cancer-causing stimulus, cells seek to avoid cancer by: synchronizing cell cycles inducing apoptosis internalizing tumor necrosis factor accelerating mitosis