The circulating B-cell repertoire is formed O after antibodies bind to antigens O by gene rearrangement in the bone marr
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The circulating B-cell repertoire is formed O after antibodies bind to antigens O by gene rearrangement in the bone marr
The circulating B-cell repertoire is formed O after antibodies bind to antigens O by gene rearrangement in the bone marrow O through exposure to the environment O by somatic mutation of antibody variable regions O by clonal deletion in the lymph nodes
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