1. Steroid hormone type I
2. Steroid hormone thpe II
3. GPCR
4. JAK-STAT
5. RTK
6. Wingless
7. Hedgehog
A. Ligand receptor is cell surface transmembrane protein
B. Pathway common to cytokines
C. Pathway common to growth factors including: EGF & IFG
D. Pathway functions in isolation of all others
E. Signaling pathway results in differential gene expression
F. Ligand is hydrophobic
G. Ligand first identified for role in Drosophila embryogenesis
H. Key step in pathway is activation of adenyl cyclase to produce cAMP
I. Pathway occurs only in Drosophila not observed in mammalian cells
J. Pathway includes Ras-Raf-Mek-Erk phosphorylation cascade
1. Steroid hormone type I 2. Steroid hormone thpe II 3. GPCR 4. JAK-STAT 5. RTK 6. Wingless 7. Hedgehog A. Ligand recept
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1. Steroid hormone type I 2. Steroid hormone thpe II 3. GPCR 4. JAK-STAT 5. RTK 6. Wingless 7. Hedgehog A. Ligand recept
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