Question 11 8 pts The graphs below show the response of a cell expressing WT receptors and one expressing mutant Nav1.7
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Question 11 8 pts The graphs below show the response of a cell expressing WT receptors and one expressing mutant Nav1.7
Question 11 8 pts The graphs below show the response of a cell expressing WT receptors and one expressing mutant Nav1.7 (sodium) receptors (F1449V). А Wild-type B F1449V 60] 155PA 60 130 PA 65PA 40 40 60pA 20 20 0 0 V. (mV) V (mv) ) -20 -20 -55 PA -50 PA 50-65 PA -40 -40 -60 -60 80 0 -80 0 20 80 100 20 80 100 40 60 Time (ms) 40 60 Time (ms) -For figures A and B: What do the numbers (in PA) tell you about the experimental setup? What difference do these figures highlight between the two cells? -Is this a gain-of-function or loss-of-function mutation?
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