Telomeres and DNA methylation have both been implicated in development and aging. Which of the following is an accurate

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Telomeres And Dna Methylation Have Both Been Implicated In Development And Aging Which Of The Following Is An Accurate 1 (119.66 KiB) Viewed 151 times

Telomeres and DNA methylation have both been implicated in development and aging. Which of the following is an accurate description of telomeres, DNA methylation patterns, development and aging? Global demethylation of DNA during early embryonic development is required to allow for accessible chromatin structure and induces pluripotency in the embryo. Telomere length is a more accurate way to determine biological age than DNA methylation patterns. When determining biological age by DNA methylation they look at the length of repeated sequences at the ends of chromosomes. Methylation present in germ cells remains present throughout the lifetime of an organism. As a person ages telomeres continue to lengthen, while DNA methylation of promoters of genes involved in pluripotency decreases.