Human-induced pluripotent stem cells (and embryonic stem cells) can be converted into functional induced neuron cells wi
Posted: Tue May 17, 2022 2:25 pm
Human-induced pluripotent stem cells (and embryonic stem cells)
can be converted into functional induced neuron cells within two
weeks by forcing the expression of a single transcription factor.
The resulting cells act like neurons, despite the cell line of
origin. They form mature pre-and postsynaptic specializations and
even integrate into existing synaptic networks when transplanted
into mouse brains. What transcription factor is able to
achieve this?
can be converted into functional induced neuron cells within two
weeks by forcing the expression of a single transcription factor.
The resulting cells act like neurons, despite the cell line of
origin. They form mature pre-and postsynaptic specializations and
even integrate into existing synaptic networks when transplanted
into mouse brains. What transcription factor is able to
achieve this?