Department of Biological Sciences BIO 452 Intermediary and Cellular Metabolism Test 2013 (Deamination, Urea cycle, Break
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Department of Biological Sciences BIO 452 Intermediary and Cellular Metabolism Test 2013 (Deamination, Urea cycle, Break
Department of Biological Sciences BIO 452 Intermediary and Cellular Metabolism Test 2013 (Deamination, Urea cycle, Breakdown of amino acids, Heme) 1. The coenzyme of transaminations is a biotin b. pyridoxi phosphate c. thiamin d. riboflavin e. NAD+ 2. The key enzyme in oxidative deamination of amino acids is: a. L-amino acid oxidase b. D-amino acid oxidase c. glutamate dehydrogenase d. serine dehydratase e. threonine dehydratase 3. Name the major amino acid released by the muscle: a. Ser b. Cys c. Ala d. branched-chain amino acids e. Asp 4. Which of the listed enzymes is located in the mitochondrial matrix ?: a. aspartate transaminase b. argininosuccinate synthetase c. ornithine transcarbamoylase d. arginase e. argininosuccinate lyase 5. Breakdown of which amino acid gives fumarate as an end product ?: a. lle b. Argc. Tyr d. Ala e. Asn 6. Which of the listed amino acids is not glycogenic?: a. Ala b. Glu c. Asp d. Cys e. Leu 7. The toxic effect of ammonia is produced b: a. inhibition of transamination b. inhibition of the mit respiratory chain c. removal of a-ketoglutarate from the TCA cycle d. inhibition of glycolysis in the brain e. inhibition of GDH activity 8. Schiff's base is: a. a compound produced by the reaction between a carboxyl group and an amino group b. a compound produced by the reaction between an aldehyde group and a OH group c. a compound produced by the reaction between an aldehyde and an amino acid d. a compound produced by the reaction between an amino acid and ATP . 9. Name the enzyme catalyzing the following reaction: L-Glu + ATP + NH3 ------> L-Gln + ADP + P a. GDH b. Threonine dehydratase c. Serine dehydratase d. Glutamine synthetase e. Glutaminase 10. Vitamin B12 absorbed in the gut is transported in the bloodstream by: a. albumin b. cobalamin c. transcobalamin d. deoxyadenosylcobalamin e. intrinsic factor
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