In rats, the following genotypes of two independently assorting autosomal genes determine coat color: A-B- is gray, A-bb

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In Rats The Following Genotypes Of Two Independently Assorting Autosomal Genes Determine Coat Color A B Is Gray A Bb 1 (68.89 KiB) Viewed 134 times

In rats, the following genotypes of two independently assorting autosomal genes determine coat color: A-B- is gray, A-bb is yellow, aaB is black, and aabb is cream. A third gene pair on a separate autosome determines whether or not any color will be produced. The CC and Cc genotypes allow color according to the A and B alleles. However, the cc genotype results in albino rats regardless of the A and B alleles present. Determine the F1 phenotypic ratio for the following cross: AaBBCC X AABbcc. a. All gray b. All albino c. 50% gray and 50% albino d. none of these This question is based on true events.... You are a pediatric oncologist. A young girl (8 years old) with a chromosome 6 deletion has been visiting your office because she has been diagnosed with a rare form of cancer, one that typically does not affect children. The nurse in your clinic alerts you that the parents mentioned that other physicians have told the parents the girl's deletion probably has nothing to do with her cancer. You are the type of physician who continually scours the literature so you can better serve your patients. Understanding the genetic origin of the girl's cancer will better help you treat it. You remember a recently published GWAS suggested variants in EXOC2, a gene located on chromosome 6, are associated with this particular form of cancer. Based on this information, how might you test if the deletion is the cause of the girl's cancer? Note: there is not one correct answer to this question. Your answer will be graded on your rationale and accuracy of the terms you use. Type your answer (1-2 sentences) below.