E The Partially Protected Dinucleotide Below Was Synthesized By The Phosphodiester Approach Suggest A Mechanism For I 1 (135.24 KiB) Viewed 60 times
E The Partially Protected Dinucleotide Below Was Synthesized By The Phosphodiester Approach Suggest A Mechanism For I 2 (135.24 KiB) Viewed 60 times
(e) The partially protected dinucleotide below was synthesized by the phosphodiester approach. Suggest a mechanism for its formation. (25) DMTIO B DMTVO B HO-P B MS-CI, Py + 0- B OH OAC OAC DMTr, 4,4'-Dimethoxytrityl MS-CI, 2,4,6-Trimethylbenzenesulfonyl chloride Py, Pyridine B = nucleobase
(e) The partially protected dinucleotide below was synthesized by the phosphodiester approach. Suggest a mechanism for its formation. (25) DMTIO B DMTVO B HO-P B MS-CI, Py + 0- B OH OAC OAC DMTr, 4,4'-Dimethoxytrityl MS-CI, 2,4,6-Trimethylbenzenesulfonyl chloride Py, Pyridine B = nucleobase
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