Which of the following are advantages of the fragment-based drug design approach versus the traditional high-throughput

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Which Of The Following Are Advantages Of The Fragment Based Drug Design Approach Versus The Traditional High Throughput 1 (73.17 KiB) Viewed 65 times

Which of the following are advantages of the fragment-based drug design approach versus the traditional high-throughput screening approach? A. Much smaller chemical libraries are needed for screening. B. Fewer synthetic steps needed to optimize hits to drug leads. C. Activity of the enzyme can be measured reliably during screening. D. Libraries consist mostly of known inhibitor and inhibitor-like compounds. E. All of the above