(a (b) Draw a curly arrow representation of the interaction of a nucleophile with a carbonyl carbon. Explain the differe

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A B Draw A Curly Arrow Representation Of The Interaction Of A Nucleophile With A Carbonyl Carbon Explain The Differe 1 (59.53 KiB) Viewed 23 times

(a (b) Draw a curly arrow representation of the interaction of a nucleophile with a carbonyl carbon. Explain the difference in the remainder of the mechanism for aldehydes/ketones and other carboxylic acid derivatives. (5 Marks) An imine can be produced from reaction of an aldehyde and a primary amine. Describe what occurs in both steps to form the imine shown below and explain why catalytic acid is required cat Pn Ph Ph Ph EN H H N (5 Marks) © The Grignard reagent ethyl magnesium bromide is selective toward one of the two carbonyl groups present in the molecule below. Which carbonyl would be most reactive, give a rationale for your answer and hence draw the reaction product. (5 Marks) Using a 'protecting group strategy show how a reaction can occur at the least reactive carbonyl while avoiding the most reactive carbonyl (5 Marks) (Total 20 Marks)