Urea Can Be Synthesized In The Human Body Following Reaction 1 2 Co2 G 2nh3 1 Nh2 2co Aq H2o 1 1 2 I Us 1 (138.86 KiB) Viewed 44 times
Urea can be synthesized in the human body following reaction (1.2): CO2(g) + 2NH3(1)→ (NH2)2CO(aq) + H2O(1) (1.2) (i) Using the data listed in Table 1 calculate the change in Gibbs free energy for the reaction (ArGº) at 37°C. Include any assumptions used in the calculations in your answer. [5 marks] (ii) Industrially the production of urea is undertaken in gas phase: CO2(g) + 2NH3(g) → (NH2)2CO(s) + H2O(g) (1.3) What is the ArGº value for this reaction under standard conditions? [2 marks] (iii) Compare the calculated ArGº values for the gas phase under standard conditions and in solution in the human body. Based on thermodynamic reasoning, why is the industrial reaction undertaken in gas phase? [2 marks] (iv) ADP is used as a catalyst in the human body to assist the formation of urea. Explain how ADP affects the direction of the reaction and the equilibrium constant? [2 marks]