15. Smokers are known to have about 50% higher CL7 than nonsmokers for theophylline. If the average observed AUC after a

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15 Smokers Are Known To Have About 50 Higher Cl7 Than Nonsmokers For Theophylline If The Average Observed Auc After A 1 (15.57 KiB) Viewed 275 times

15. Smokers are known to have about 50% higher CL7 than nonsmokers for theophylline. If the average observed AUC after administration of 300 mg IV theophylline in nonsmokers is 100 mg.hr/L, what is the expected AUC in smokers after administration of the same 300 mg dose. Assume linear pharmacokinetics