a. The compound shown below shows good activity against its target in in vitro studies. When in in vivo tests were carri
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a. The compound shown below shows good activity against its target in in vitro studies. When in in vivo tests were carri
a. The compound shown below shows good activity against its target in in vitro studies. When in in vivo tests were carried out, the drug showed poor activity when it was administered orally. Explain these observations and suggest a strategy to overcome this issue in vivo, making reference to the structure. [5 marks] HO HO N
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