Question 4 A group of 100 healthy women was followed prospectively for 10 years. All subjects entered the study on Janua
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Question 4 A group of 100 healthy women was followed prospectively for 10 years. All subjects entered the study on Janua
Question 4 A group of 100 healthy women was followed prospectively for 10 years. All subjects entered the study on January 1, 1996 and all women were followed until December 31, 2005. None were lost to follow-up. During this period, 10 subjects were diagnosed with breast cancer, but they all survived to the end of the study. The time at which these 10 subjects developed cancer is shown in this table. Assume that each diagnosis occurred exactly half way through the year. For example, Subject 9 was cancer free for the first half of the year. Subject 1996 1997 1998 1999 2000 2001 2002 2003 2004 2005 cancer 2 3 cancer cancer 4 cancer 5 cancer cancer 6 7 cancer 8 cancer 9 Cancer Cancer 10 Calculate and interpret the following measures of disease frequency: a. Prevalence (%) of breast cancer "survivors" on January 1, 2002. Don't forget to include the women who never got sick as part of the denominator. [6] b. Prevalence %) of breast cancer "survivors" on December 31, 2005. Don't forget to include the women who never got sick as part of the denominator. [6] 4 Name c. Cumulative incidence %) of breast cancer over the 10-year study period. Don't forget to include the women who never got sick as part of the denominator. [6] d. Incidence rate of breast cancer over the 10-year study period. Don't forget to include the person-time of the women who never got sick as part of the denominator. [12]